Retraction for Kalia et al., Infect. Immun. 69 (8) 4858-4869.
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 Previous Article

Infection and Immunity, October 2009, p. 4688, Vol. 77, No. 10
0019-9567/09/$08.00+0     doi:10.1128/IAI.00966-09

RETRACTION

Directional Gene Movement from Human-Pathogenic to Commensal-Like Streptococci

Awdhesh Kalia, Mark C. Enright, Brian G. Spratt, and Debra E. Bessen

Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, and Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, and Department of Infectious Disease Epidemiology, Imperial College School of Medicine, University of London, St. Mary's Campus, London W2 IPG, United Kingdom

Volume 69, no. 8, p. 4858-4869, 2001: We retract the article.

We have uncertainties as to the overall strength of the main conclusion on interspecies gene transfer of highly divergent housekeeping gene alleles from group A streptococci (GAS) to group C and G streptococci (GCS/GGS), due to an inability to replicate some of the original GCS/GGS-derived sequence data. The reasons may be that (i) the GCS/GGS DNA template used for PCR amplification was contaminated with trace amounts of GAS DNA and/or (ii) there are subtleties with the PCR amplification conditions that could not be replicated due to changes in commercial reagents, thermal cyclers, etc. A clear-cut resolution of this matter may require whole-genome sequencing and assembly for at least a few GCS/GGS strains.

Infection and Immunity, October 2009, p. 4688, Vol. 77, No. 10
0019-9567/09/$08.00+0     doi:10.1128/IAI.00966-09





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