To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
Infect. Immun. 2008 76: 3359. [Full Text] [PDF] [Reprints and Permissions]  

Minireviews:

Geraldine O. Canny and Beth A. McCormick

Bacteria in the Intestine, Helpful Residents or Enemies from Within?
Infect. Immun. 2008 76: 3360-3373. [Full Text] [PDF] [Reprints and Permissions]  

Molecular Pathogenesis:

Alan G. Barbour, Algimantas Jasinskas, Matthew A. Kayala, D. Huw Davies, Allen C. Steere, Pierre Baldi, and Philip L. Felgner

A Genome-Wide Proteome Array Reveals a Limited Set of Immunogens in Natural Infections of Humans and White-Footed Mice with Borrelia burgdorferi
Infect. Immun. 2008 76: 3374-3389. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Traci L. Kinkel and Kevin S. McIver

CcpA-Mediated Repression of Streptolysin S Expression and Virulence in the Group A Streptococcus
Infect. Immun. 2008 76: 3451-3463. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Mélissa Caza, François Lépine, Sylvain Milot, and Charles M. Dozois

Specific Roles of the iroBCDEN Genes in Virulence of an Avian Pathogenic Escherichia coli O78 Strain and in Production of Salmochelins
Infect. Immun. 2008 76: 3539-3549. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Angela H. Nobbs, Roberto Rosini, C. Daniela Rinaudo, Domenico Maione, Guido Grandi, and John L. Telford

Sortase A Utilizes an Ancillary Protein Anchor for Efficient Cell Wall Anchoring of Pili in Streptococcus agalactiae
Infect. Immun. 2008 76: 3550-3560. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maria P. Isaza, Matthew S. Duncan, Jeffrey B. Kaplan, and Scott C. Kachlany

Screen for Leukotoxin Mutants in Aggregatibacter actinomycetemcomitans: Genes of the Phosphotransferase System Are Required for Leukotoxin Biosynthesis
Infect. Immun. 2008 76: 3561-3568. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karen H. L. Lim, Christopher E. Jones, Rachel N. vanden Hoven, Jennifer L. Edwards, Megan L. Falsetta, Michael A. Apicella, Michael P. Jennings, and Alastair G. McEwan

Metal Binding Specificity of the MntABC Permease of Neisseria gonorrhoeae and Its Influence on Bacterial Growth and Interaction with Cervical Epithelial Cells
Infect. Immun. 2008 76: 3569-3576. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Lotisha E. Garvin, Margaret C. Bash, Christine Keys, Douglas M. Warner, Sanjay Ram, William M. Shafer, and Ann E. Jerse

Phenotypic and Genotypic Analyses of Neisseria gonorrhoeae Isolates That Express Frequently Recovered PorB PIA Variable Region Types Suggest that Certain P1a Porin Sequences Confer a Selective Advantage for Urogenital Tract Infection
Infect. Immun. 2008 76: 3700-3709. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katharina Beiter, Florian Wartha, Robert Hurwitz, Staffan Normark, Arturo Zychlinsky, and Birgitta Henriques-Normark

The Capsule Sensitizes Streptococcus pneumoniae to -Defensins Human Neutrophil Proteins 1 to 3
Infect. Immun. 2008 76: 3710-3716. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Justin L. Spinner, Jennifer A. Cundiff, and Scott D. Kobayashi

Yersinia pestis Type III Secretion System-Dependent Inhibition of Human Polymorphonuclear Leukocyte Function
Infect. Immun. 2008 76: 3754-3760. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

James G. Smedley, III, Juliann Saputo, Jacquelyn C. Parker, Mariano E. Fernandez-Miyakawa, Susan L. Robertson, Bruce A. McClane, and Francisco A. Uzal

Noncytotoxic Clostridium perfringens Enterotoxin (CPE) Variants Localize CPE Intestinal Binding and Demonstrate a Relationship between CPE-Induced Cytotoxicity and Enterotoxicity
Infect. Immun. 2008 76: 3793-3800. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions:

Jennifer M. Lamb-Rosteski, Lisa D. Kalischuk, G. Douglas Inglis, and Andre G. Buret

Epidermal Growth Factor Inhibits Campylobacter jejuni-Induced Claudin-4 Disruption, Loss of Epithelial Barrier Function, and Escherichia coli Translocation
Infect. Immun. 2008 76: 3390-3398. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Linda Bönquist, Helena Lindgren, Igor Golovliov, Tina Guina, and Anders Sjöstedt

MglA and Igl Proteins Contribute to the Modulation of Francisella tularensis Live Vaccine Strain-Containing Phagosomes in Murine Macrophages
Infect. Immun. 2008 76: 3502-3510. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Takashi Shimizu, Yutaka Kida, and Koichi Kuwano

A Triacylated Lipoprotein from Mycoplasma genitalium Activates NF-B through Toll-Like Receptor 1 (TLR1) and TLR2
Infect. Immun. 2008 76: 3672-3678. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jun Fujii, Katie Wood, Fumiko Matsuda, Benedito A. Carneiro-Filho, Keilo H. Schlegel, Takashi Yutsudo, Beth Binnington-Boyd, Clifford A. Lingwood, Fumiko Obata, Kwang S. Kim, Shin-ichi Yoshida, and Tom Obrig

Shiga Toxin 2 Causes Apoptosis in Human Brain Microvascular Endothelial Cells via C/EBP Homologous Protein
Infect. Immun. 2008 76: 3679-3689. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bacterial Infections:

Linda Johansson, Pontus Thulin, Parham Sendi, Erika Hertzén, Adam Linder, Per Åkesson, Donald E. Low, Birgitta Agerberth, and Anna Norrby-Teglund

Cathelicidin LL-37 in Severe Streptococcus pyogenes Soft Tissue Infections in Humans
Infect. Immun. 2008 76: 3399-3404. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gregory W. Martens, Meltem Cevik Arikan, Jinhee Lee, Fucheng Ren, Therese Vallerskog, and Hardy Kornfeld

Hypercholesterolemia Impairs Immunity to Tuberculosis
Infect. Immun. 2008 76: 3464-3472. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anna Brotcke and Denise M. Monack

Identification of fevR, a Novel Regulator of Virulence Gene Expression in Francisella novicida
Infect. Immun. 2008 76: 3473-3480. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Thomas A. Russo, Janet M. Beanan, Ruth Olson, Ulrike MacDonald, Nicole R. Luke, Steven R. Gill, and Anthony A. Campagnari

Rat Pneumonia and Soft-Tissue Infection Models for the Study of Acinetobacter baumannii Biology
Infect. Immun. 2008 76: 3577-3586. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nahuel Fittipaldi, Tsutomu Sekizaki, Daisuke Takamatsu, Josée Harel, María de la Cruz Domínguez-Punaro, Sonja Von Aulock, Christian Draing, Corinne Marois, Marylène Kobisch, and Marcelo Gottschalk

D-Alanylation of Lipoteichoic Acid Contributes to the Virulence of Streptococcus suis
Infect. Immun. 2008 76: 3587-3594. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Xiaowen R. Bina, Daniele Provenzano, Nathalie Nguyen, and James E. Bina

Vibrio cholerae RND Family Efflux Systems Are Required for Antimicrobial Resistance, Optimal Virulence Factor Production, and Colonization of the Infant Mouse Small Intestine
Infect. Immun. 2008 76: 3595-3605. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nrusingh P. Mohapatra, Shilpa Soni, Thomas J. Reilly, Jirong Liu, Karl E. Klose, and John S. Gunn

Combined Deletion of Four Francisella novicida Acid Phosphatases Attenuates Virulence and Macrophage Vacuolar Escape
Infect. Immun. 2008 76: 3690-3699. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Jeffrey M. Jordan, Michael E. Woods, Juan Olano, and David H. Walker

The Absence of Toll-Like Receptor 4 Signaling in C3H/HeJ Mice Predisposes Them to Overwhelming Rickettsial Infection and Decreased Protective Th1 Responses
Infect. Immun. 2008 76: 3717-3724. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Liana Steeghs, A. Marijke Keestra, Andries van Mourik, Heli Uronen-Hansson, Peter van der Ley, Robin Callard, Nigel Klein, and Jos P. M. van Putten

Differential Activation of Human and Mouse Toll-Like Receptor 4 by the Adjuvant Candidate LpxL1 of Neisseria meningitidis
Infect. Immun. 2008 76: 3801-3807. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lionel Piroth, Yok-Ai Que, Eleonora Widmer, Alexandre Panchaud, Stéphane Piu, José M. Entenza, and Philippe Moreillon

The Fibrinogen- and Fibronectin-Binding Domains of Staphylococcus aureus Fibronectin-Binding Protein A Synergistically Promote Endothelial Invasion and Experimental Endocarditis
Infect. Immun. 2008 76: 3824-3831. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Host Response and Inflammation:

Haibin Huang, Mingqun Lin, Xueqi Wang, Takane Kikuchi, Heather Mottaz, Angela Norbeck, and Yasuko Rikihisa

Proteomic Analysis of and Immune Responses to Ehrlichia chaffeensis Lipoproteins
Infect. Immun. 2008 76: 3405-3414. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

R. D. Nogueira, W. F. King, G. Gunda, S. Culshaw, M. A. Taubman, R. O. Mattos-Graner, and D. J. Smith

Mutans Streptococcal Infection Induces Salivary Antibody to Virulence Proteins and Associated Functional Domains
Infect. Immun. 2008 76: 3606-3613. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karen L. Mumy, Jeffrey D. Bien, Michael A. Pazos, Karsten Gronert, Bryan P. Hurley, and Beth A. McCormick

Distinct Isoforms of Phospholipase A₂ Mediate the Ability of Salmonella enterica Serotype Typhimurium and Shigella flexneri To Induce the Transepithelial Migration of Neutrophils
Infect. Immun. 2008 76: 3614-3627. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Arthur Blum, Tommy Setiawan, Long Hang, Korynn Stoyanoff, and Joel V. Weinstock

Interleukin-12 (IL-12) and IL-23 Induction of Substance P Synthesis in Murine T Cells and Macrophages Is Subject to IL-10 and Transforming Growth Factor β Regulation
Infect. Immun. 2008 76: 3651-3656. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Samuel B. Ferreira, Jr., Ana Paula F. Trombone, Carlos E. Repeke, Cristina R. Cardoso, Walter Martins, Jr., Carlos F. Santos, Paula Cristina Trevilatto, Mario J. Ávila-Campos, Ana Paula Campanelli, João S. Silva, and Gustavo P. Garlet

An Interleukin-1β (IL-1β) Single-Nucleotide Polymorphism at Position 3954 and Red Complex Periodontopathogens Independently and Additively Modulate the Levels of IL-1β in Diseased Periodontal Tissues
Infect. Immun. 2008 76: 3725-3734. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fungal and Parasitic Infections:

Zhongyu Li, Ding Chen, Youmin Zhong, Shiping Wang, and Guangming Zhong

The Chlamydial Plasmid-Encoded Protein pgp3 Is Secreted into the Cytosol of Chlamydia-Infected Cells
Infect. Immun. 2008 76: 3415-3428. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lisa Y. Chiang, Donald C. Sheppard, Fabrice N. Gravelat, Thomas F. Patterson, and Scott G. Filler

Aspergillus fumigatus Stimulates Leukocyte Adhesion Molecules and Cytokine Production by Endothelial Cells In Vitro and during Invasive Pulmonary Disease
Infect. Immun. 2008 76: 3429-3438. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paul J. Christensen, Angela M. Preston, Tony Ling, Ming Du, W. Bradley Fields, Jeffrey L. Curtis, and James M. Beck

Pneumocystis murina Infection and Cigarette Smoke Exposure Interact To Cause Increased Organism Burden, Development of Airspace Enlargement, and Pulmonary Inflammation in Mice
Infect. Immun. 2008 76: 3481-3490. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Manlio Di Cristina, Daniela Marocco, Roberto Galizi, Carla Proietti, Roberta Spaccapelo, and Andrea Crisanti

Temporal and Spatial Distribution of Toxoplasma gondii Differentiation into Bradyzoites and Tissue Cyst Formation In Vivo
Infect. Immun. 2008 76: 3491-3501. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joshua J. Reece, Mark C. Siracusa, Teresa L. Southard, Cory F. Brayton, Joseph F. Urban, Jr., and Alan L. Scott

Hookworm-Induced Persistent Changes to the Immunological Environment of the Lung
Infect. Immun. 2008 76: 3511-3524. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Massaro W. Ueti, Guy H. Palmer, Glen A. Scoles, Lowell S. Kappmeyer, and Donald P. Knowles

Persistently Infected Horses Are Reservoirs for Intrastadial Tick-Borne Transmission of the Apicomplexan Parasite Babesia equi
Infect. Immun. 2008 76: 3525-3529. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bo Lu and Mercio PereiraPerrin

A Novel Immunoprecipitation Strategy Identifies a Unique Functional Mimic of the Glial Cell Line-Derived Neurotrophic Factor Family Ligands in the Pathogen Trypanosoma cruzi
Infect. Immun. 2008 76: 3530-3538. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sumana Chakravarty, G. Christian Baldeviano, Michael G. Overstreet, and Fidel Zavala

Effector CD8⁺ T Lymphocytes against Liver Stages of Plasmodium yoelii Do Not Require Gamma Interferon for Antiparasite Activity
Infect. Immun. 2008 76: 3628-3631. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fabrice N. Gravelat, Thomas Doedt, Lisa Y. Chiang, Hong Liu, Scott G. Filler, Thomas F. Patterson, and Donald C. Sheppard

In Vivo Analysis of Aspergillus fumigatus Developmental Gene Expression Determined by Real-Time Reverse Transcription-PCR
Infect. Immun. 2008 76: 3632-3639. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dan Takeuchi, Vickie C. Jones, Makiko Kobayashi, and Fujio Suzuki

Cooperative Role of Macrophages and Neutrophils in Host Antiprotozoan Resistance in Mice Acutely Infected with Cryptosporidium parvum
Infect. Immun. 2008 76: 3657-3663. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Naheed Choudhry, Mona Bajaj-Elliott, and Vincent McDonald

The Terminal Sialic Acid of Glycoconjugates on the Surface of Intestinal Epithelial Cells Activates Excystation of Cryptosporidium parvum
Infect. Immun. 2008 76: 3735-3741. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jin Liu, Shinichiro Enomoto, Cheryl A. Lancto, Mitchell S. Abrahamsen, and Mark S. Rutherford

Inhibition of Apoptosis in Cryptosporidium parvum-Infected Intestinal Epithelial Cells Is Dependent on Survivin
Infect. Immun. 2008 76: 3784-3792. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Microbial Immunity and Vaccines:

Lin Yan, Jin Qiu, Jianbo Chen, Bridgett Ryan-Payseur, Dan Huang, Yunqi Wang, Lijun Rong, Jody A. Melton-Witt, Nancy E. Freitag, and Zheng W. Chen

Selected prfA* Mutations in Recombinant Attenuated Listeria monocytogenes Strains Augment Expression of Foreign Immunogens and Enhance Vaccine-Elicited Humoral and Cellular Immune Responses
Infect. Immun. 2008 76: 3439-3450. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Philip A. Arlen, Michael Singleton, Jeffrey J. Adamovicz, Yi Ding, Abdolreza Davoodi-Semiromi, and Henry Daniell

Effective Plague Vaccination via Oral Delivery of Plant Cells Expressing F1-V Antigens in Chloroplasts
Infect. Immun. 2008 76: 3640-3650. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jason F. Huntley, Patrick G. Conley, David A. Rasko, Kayla E. Hagman, Michael A. Apicella, and Michael V. Norgard

Native Outer Membrane Proteins Protect Mice against Pulmonary Challenge with Virulent Type A Francisella tularensis
Infect. Immun. 2008 76: 3664-3671. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter Lauer, Bill Hanson, Edward E. Lemmens, Weiqun Liu, William S. Luckett, Meredith L. Leong, Heather E. Allen, Justin Skoble, Keith S. Bahjat, Nancy E. Freitag, Dirk G. Brockstedt, and Thomas W. Dubensky, Jr.

Constitutive Activation of the PrfA Regulon Enhances the Potency of Vaccines Based on Live-Attenuated and Killed but Metabolically Active Listeria monocytogenes Strains
Infect. Immun. 2008 76: 3742-3753. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jose Yuste, Ashwin Sen, Lennart Truedsson, Göran Jönsson, Liang-Seah Tay, Catherine Hyams, Helen E. Baxendale, Fiona Goldblatt, Marina Botto, and Jeremy S. Brown

Impaired Opsonization with C3b and Phagocytosis of Streptococcus pneumoniae in Sera from Subjects with Defects in the Classical Complement Pathway
Infect. Immun. 2008 76: 3761-3770. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Simon Clark, Martin L. Cross, Allan Nadian, Julia Vipond, Pinar Court, Ann Williams, R. Glyn Hewinson, Frank E. Aldwell, and Mark A. Chambers

Oral Vaccination of Guinea Pigs with a Mycobacterium bovis Bacillus Calmette-Guérin Vaccine in a Lipid Matrix Protects against Aerosol Infection with Virulent M. bovis
Infect. Immun. 2008 76: 3771-3776. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wen-Wei Zhang and Greg Matlashewski

Immunization with a Toll-Like Receptor 7 and/or 8 Agonist Vaccine Adjuvant Increases Protective Immunity against Leishmania major in BALB/c Mice
Infect. Immun. 2008 76: 3777-3783. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thierry Blisnick, Patrick Ave, Michel Huerre, Elisabeth Carniel, and Christian E. Demeure

Oral Vaccination against Bubonic Plague Using a Live Avirulent Yersinia pseudotuberculosis Strain
Infect. Immun. 2008 76: 3808-3816. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Solabomi A. Ogun, Laurence Dumon-Seignovert, Jean-Baptiste Marchand, Anthony A. Holder, and Fergal Hill

The Oligomerization Domain of C4-Binding Protein (C4bp) Acts as an Adjuvant, and the Fusion Protein Comprised of the 19-Kilodalton Merozoite Surface Protein 1 Fused with the Murine C4bp Domain Protects Mice against Malaria
Infect. Immun. 2008 76: 3817-3823. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.